This latest-generation retinoid serum acts specifically on the nuclear receptors of skin cells, stimulating renewal, regeneration and the synthesis of new extracellular matrix structures. It helps to even out skin microrelief and tone, visibly refine pores, support normal keratinisation and reduce the appearance of breakouts. Skin elasticity and hydration are restored, the complexion looks visibly brighter and fine lines are smoothed.
The serum contains two unique actives. HPR retinoid of the latest generation is one of the most advanced over-the-counter retinoids for skin renewal and is well tolerated, with a very low irritation potential. Renovage complex helps to densify the dermis and restore its turgor by stabilising telomeres in cell DNA. The blend of sweet almond and grape seed oils saturates the skin with antioxidants, helping to protect tissues from oxidative stress. The serum has a light oily texture, absorbs well and leaves no film on the skin surface.
SUITABLE FOR:
- Skin showing visible signs of ageing, and as a preventive routine
- Blemish-prone skin, as part of a professional programme
- Uneven tone and hyperpigmentation of varied origin
NOT RECOMMENDED FOR:
- Pregnancy and breastfeeding.
- Compromised skin integrity: wounds, burns, active inflammation in the application area.
- Dermatoses in an active flare: rosacea, eczema, atopic and seborrhoeic dermatitis.
- Concurrent use of other retinoids, whether topical (retinol, adapalene, tretinoin) or systemic.
FAQ
Can HPR SERUM be used with device-based treatments?
No. HPR SERUM has an oil base, which does not provide the required conductivity and is not compatible with the gel media designed for device-based treatments. In addition, energy input โ primarily thermal and UV โ may compromise the stability of the retinoid molecule. For device-based procedures, use gel serums or sterile mesotherapy cocktails from Reneo Cosmetics.
Can HPR SERUM be combined with a course of peels, and how should the two be spaced?
Yes, the combination makes sense: the serum works well in comprehensive programmes, in particular with Peel-Expert Shine for the correction of hyperpigmentation. The only question is the interval, and it depends on the depth of the peel.
- Superficial peels (including Peel-Expert) โ suspend on the day of the procedure and resume the following day.
- A course of TCA peels โ suspend 48 hours before the procedure and for 2โ3 weeks, until the skin has fully recovered.
Daily sun protection is essential throughout the course.
How should HPR SERUM be combined with acne therapy?
HPR SERUM is a professional skincare product, not an acne therapy, and it does not replace a treatment regimen prescribed by a physician. Its role in working with blemish-prone skin is to support normal keratinisation, reduce follicular hyperkeratosis and address post-acne marks and uneven tone.
The optimal scenario is the maintenance phase, once active therapy has been completed and in agreement with the treating physician. Introduce gradually, following the basic schedule: once every three days โ every other day โ daily.
The serum is not used:
- During an active inflammatory process, when topical therapy in combination with an antibiotic is indicated;
- In severe forms of acne against a background of systemic retinoid therapy โ this is excluded (see ‘Not recommended for’).
If the skin is already adapted to retinoids, can application start at daily frequency?
Even where there is prior experience of retinoids, the serum should be introduced gradually โ otherwise the risk of a retinoid reaction increases. Advise the patient accordingly, as with the prescription of any topical retinoid.
At the first signs โ mild tingling, discomfort, dryness, a feeling of tightness โ reduce the frequency of application by one step:
- Daily โ every other day;
- Every other day โ once every 2โ3 days.
If the signs persist, return to the previous step for a further week. The product does not need to be discontinued.
Can HPR SERUM be applied in the morning in autumn or winter? The sun is no longer so strong.
Yes, HPR retinoid is not phototoxic. However, moving to twice-daily application is advisable only once the skin is fully adapted to the evening routine, and with daily sun protection regardless of the season.
Also consider the texture: the serum is oily and may not be comfortable enough for daytime use, particularly on oily skin.
Can the retinoid serum be combined with an azelaic acid cream, or is it better to alternate days?
The combination is acceptable where indicated, but both products should be introduced gradually. A workable scenario is the azelaic acid cream daily and the serum every other day; the exact schedule depends on the skin’s resources and tolerance.
Will HPR SERUM dry the skin from the first applications? Should moisturising products be introduced straight away?
Yes, a cream is needed from the outset: 10โ15 minutes after the serum, always seal the skin with a cream. For oily skin โ P221/H222 Lipid Balancing Light Cream; for an anti-ageing effect โ P194/H195 Renew Lifting Cream.
Amy Trainor –
I tried it, I really liked the serum, in the morning the skin is stretched, radiant
Karla Penfold –
The serum is awesome! The effect can be felt immediately. The skin looks smoothed and nourished!
Diana Shaw –
The serum is very good! The skin really becomes radiant, tightened, moisturized and smooth! Does not cause any irritation, dryness, even for sensitive skin. I recommend it!
Layla Buckley –
The best retinol serum I have ever tested on myself. The skin looks fuller and with an attractive glow. I recommend it.